You can’t poison your body and expect microbes to save you. They mirror your internal environment; they don’t override it.
The composition and function of your microbiome are shaped by what you eat, how you sleep, the toxins you're exposed to, your stress levels, movement, and overall lifestyle. It adapts to your internal state — if you're unwell, your microbiome will show it.
A balanced microbiome supports health: digestion, inflammation control, neurotransmitter production. But it can’t undo the damage caused by chronic toxic inputs. You can’t expect microbes to “heal” what you're still harming.
Flood your body with sugar, alcohol, chemicals, or stress, and the microbiome shifts toward dysbiosis — an overgrowth of harmful bacteria. In that state, it no longer protects you. It contributes to disease.
Dysbiosis = Inflammation Trigger
Weakens the gut lining, allowing endotoxins (like LPS) to leak into the bloodstream
Overstimulates the immune system
Fuels chronic low-grade inflammation — linked to obesity, diabetes, autoimmune conditions, and depression
In mouse studies, germ-free mice (raised without any microbiome) must be given extra vitamins, SCFAs, and special diets to stay alive — and even then, they’re underdeveloped, immunologically impaired, and metabolically fragile.
If you had no microbiome at all, your ability to absorb and process nutrients would be severely impaired — even if your gut lining and organs were otherwise intact.
While you could technically survive for a time, your system would slowly break down due to cumulative deficiencies and dysfunction.
Gut lining breakdown = malabsorption + inflammation Without microbial support:
The mucosal barrier degrades Gut permeability increases (leaky gut) Nutrients may pass through too quickly or trigger immune reactions This leads to chronic malabsorption and food sensitivities
In short: Without a microbiome, you'd be eating — but not truly nourishing your body.
The gut is a competitive ecosystem — trillions of microbes fighting for space.
Most probiotics don’t even survive the stomach’s acidity. Those that do face an entrenched population that isn’t exactly welcoming. You can’t just throw in a few strains and expect them to rebuild a system.
Now add modern diets: loaded with preservatives — substances specifically designed to kill bacteria. That includes the good ones. These chemicals quietly disrupt the microbial balance and fuel dysbiosis.
Preservatives are antimicrobial. They don’t just keep food from spoiling — they keep you from thriving.
And while antibiotics and preservatives differ in purpose, their accumulative effect can resemble long-term antibiotic damage — especially when your internal systems are already weakened.
Meanwhile, many “natural” probiotic supplements are owned by the same conglomerates that push the poisons. It’s a brilliant business model: sell you the problem, then profit off the illusion of a cure.
Probiotics? It’s like trying to sweeten the ocean with a pinch of sugar.
A Deeper Truth
Think of your gut like a city
One thief (antibiotic) won’t destroy it.
But if the police (immune system) are asleep, the infrastructure (cell energy) is crumbling, and supplies (nutrients) are contaminated… even a small problem becomes a disaster.
No single antibiotic or additive destroys your microbiome in one go — but the terrain matters. If your immune system, mitochondria, and detox systems are already weakened, the damage becomes long-term.
Let’s break it down:
1. The microbiome is resilient — but not invincible
Like a rainforest, it can recover — unless the assaults are constant.
Stress, poor diet, toxins, and inflammation weaken its regenerative capacity.
Antibiotics and preservatives are just repeated microbial insults. Over time, they shrink the ecosystem.
2. The terrain is everything
The microbiome interacts with your immune, metabolic, and nervous systems.
If the liver is overwhelmed, the mitochondria are depleted, and the immune system is confused:
Good microbes won’t survive.
Pathogens will thrive.
3. Toxins act systemically, not just in the gut
Glyphosate, plastics, heavy metals, endocrine disruptors…
Disrupt mitochondrial function
Impair hormone signaling
Suppress immune tolerance
Even if they don’t “kill” bacteria, they poison the system the bacteria rely on.
So what about fecal transplants (FMT, fecal microbiota transplantation)?
FMT doesn’t fix the terrain.
It doesn’t stop toxic habits.
It doesn’t rebuild the immune system.
Most studies and clinics don’t control for lifestyle, so it’s unclear whether the transplant, the terrain, or both created improvement. FMT still has to prove that it works without parallel changes in diet, toxin load, or lifestyle.
If there is any true benefit, the results can’t be sustained — because the same hostile terrain will just destroy or mutate the new microbes.
🚨Here is a killer thought🚨
Animals like rabbits or goats can eat rough, fibrous, even toxic plants because their entire biology is designed for it — from their teeth, saliva, and gut length, to their microbiome and enzymatic profile. Their microbiota works with their biology, not against it.
So yeah, you could technically transplant rabbit gut bacteria into a human… But here’s what happens:
Host compatibility: Their microbes evolved to work in that animal’s system. In humans, they likely won’t colonize properly or may even trigger immune reactions. Your body might just flush them out — or worse, treat them as invaders.
Environment mismatch: If your diet, pH, enzymes, immune system, and overall gut environment don’t match the microbes’ needs, they’ll die off. A healthy rabbit diet is not a healthy human diet.
Systems context: Microbes don’t act alone. They're part of a feedback loop. Transplanting foreign bacteria without changing the systemic conditions (diet, toxins, inflammation, hormones) doesn’t fix the root issue. It's like swapping out flowers in a poisoned garden and expecting them to bloom.
The reality:
1. The terrain decides everything
You can introduce a million perfect microbes into a damaged gut — they won’t survive.
In a toxic body, new bacteria die, mutate, or misbehave.
2. It’s not plug-and-play
You're not copying a microbiome like a USB drive.
You're trying to seed a complex, living culture in damaged soil.
3. It can backfire
In people with leaky gut or autoimmune issues, a sudden microbial shift can trigger flares, worsen inflammation, or cause new imbalances.
You can’t transplant health into a sick body. You have to rebuild the terrain — the energy, the immune rhythm, the detox pathways. Lifestyle is the true cure.
And not in the shallow “eat clean” way — but in the deep, systemic sense:
Real food over chemicals
Restorative sleep
Nervous system regulation
Detoxifying your environment
Movement, sunlight, nature, human connection
These are the signals that tell your body:
“You’re safe now. You can heal.”
It’s not the pill, the probiotic, or the transplant.
It’s the terrain. It’s your choices. That’s the cure.
This logic also applies to vaccinations:
If you believe in the science, vaccines only “work” by activating a functioning immune system. But if the immune system is functioning — if you're alive and healing — then you don’t need those products to begin with. Because healing isn’t outsourced.
Stop flooding your body with toxins, stress, and excess food. Let it breathe. Let it repair. And it will — if you stop getting in its way.
Final Thought:
Your body already holds the tools to rebuild your health — and to restore the mirror of that health: your microbiome. You don’t need someone else’s microbes to heal.
What you need is to stop poisoning your terrain. Do that — and your body will do the rest.
Great article, Manu!
https://x.com/wideawake_media/status/1918571643170967930?s=46&t=8lKsot7pcdmGUGcY7FMq6Q